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Synaptophysin anticorps (AA 224-313) (CF®555)

L’anticorps Souris Monoclonal anti-Synaptophysin a été validé pour IHC et IHC (fp). Il convient pour détecter Synaptophysin dans des échantillons de Humain.
N° du produit ABIN7660487

Aperçu rapide pour Synaptophysin anticorps (AA 224-313) (CF®555) (ABIN7660487)

Antigène

Voir toutes Synaptophysin (SYP) Anticorps
Synaptophysin (SYP)

Reactivité

  • 91
  • 60
  • 59
  • 11
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  • 6
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
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  • 1
  • 1
Humain

Hôte

  • 58
  • 48
  • 3
  • 1
Souris

Clonalité

  • 64
  • 46
Monoclonal

Conjugué

  • 79
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
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Cet anticorp Synaptophysin est conjugé à/à la CF®555

Application

  • 76
  • 60
  • 30
  • 21
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  • 11
  • 6
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  • 1
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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone

SYP-3551
  • Épitope

    • 15
    • 12
    • 9
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 224-313

    Fonction

    Synaptophysin (Neuroendocrine Marker)(SYP/3551), CF555 conjugate

    Attributs du produit

    This monospecific monoclonal antibody recognizes a protein of 38 kDa that is identified as synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Recombinant fragment (around aa 224-313) of human Synaptophysin (SYP) protein

    Isotype

    IgG1, kappa
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Commentaires

    Positive Control: HepG2, SH-SY-5Y, HeLa or Y79 cells. Pancreas, Cerebellum or Pheochromocytoma.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1 mg/mL

    Buffer

    PBS, 0.1 % BSA, 0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light

    Stock

    4 °C

    Stockage commentaire

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    Date de péremption

    24 months
  • Antigène

    Synaptophysin (SYP)

    Autre désignation

    Synaptophysin

    Sujet

    Synonyms: Major synaptic vesicle protein p38, MRX96, MRXSYP, Syn p38, Syp, SYPH

    Gene Symbol: MSH2

    Poids moléculaire

    38 kDa

    ID gène

    6855

    Pathways

    Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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